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P. aeruginosa

Pseudomonas aeruginosa—Demonstrated in vitro activity in the presence of some AmpC β-lactamases and against certain strains lacking OprD1

A chart describing P.aeruginosa in the presence of AmpC B-lactamases
  • AVYCAZ is not active against bacteria that produce metallo-β-lactamases and may not have activity against Gram-negative bacteria that overexpress efflux pumps or have porin mutations1

No cross-resistance with other classes of antimicrobials has been identified1

  • Some isolates resistant to other cephalosporins—including ceftazidime—and to carbapenems may be susceptible to AVYCAZ1