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Adverse reactions in cIAI
and cUTI

cIAI

INCIDENCE OF SELECTED ADVERSE REACTIONS OCCURRING IN 1% OR MORE OF PATIENTS RECEIVING AVYCAZ IN THE PHASE 3 cIAI TRIAL1

Chart of selected adverse reactions in 1% or more of patients in Phase 3 cIAI trial

*2.5 grams (ceftazidime 2 grams and avibactam 0.5 grams) IV over 120 minutes every 8 hours (with metronidazole 0.5 grams IV every 8 hours).

1 gram IV over 30 minutes every 8 hours.

cUTI

INCIDENCE OF SELECTED ADVERSE DRUG REACTIONS OCCURRING IN 1% OR MORE OF PATIENTS RECEIVING AVYCAZ IN TRIAL 11

Chart of selected adverse drug reactions in 5% or more of patients in the Phase 2 cUTI trial

2.5 grams (ceftazidime 2 grams and avibactam 0.5 grams) IV over 120 minutes every 8 hours.

§0.5 grams IV over 60 minutes every 8 hours.

IV, intravenous.